Principal vs. Non-principal multiplex

The Principal multiplex must be designated whenever there is a secondary, non-principal, multiplex within the same system frame. The System Parameters dialog will be coupled only to the zone layers, components, and controllers in the Principal multiplex.
The inclusion of  secondary, non-principal, multiplex within the same system frame is not permitted for single-zone (system types 03 and 04) or packaged terminal units (system types 01 and 02) which are not coupled to a DOAS (as is system types 09j and 09k).
The inclusion of  secondary, non-principal, multiplex within the same system frame should be necessary only when there are multiple zones that must be included on the same airside network either before or after, rather than in parallel to, the main set of zones on the system. The network below provides an example of this.  
 


The same message is also displayed if the principal multiplex is deleted, de-multiplexed, or moved out from the system.
‘ One or more of the airside networks in this ApacheHVAC file cannot be upgraded as required for use with the ISM System Parameters user interface. These are airside system networks of type 03 or 04, which are meant to be ‘packaged single-zone’ systems. For this system configuration, the upgrade requires that there is not more than one multiplex within the system frame. For single-zone systems, secondary multiplexes can be connected to a primary multiplex, but must be set up either as separate systems (within a separate system frame) or at very least outside of the system frame for the packaged single-zone system.’